If you are searching for a download, be extremely cautious of "Install Wizard" files that ask you to turn off your antivirus or install additional software. Since there is no official PC executable file for this game, almost all "direct download" sites for 2010 FIFA World Cup South Africa are high-risk vectors for malware.
This is the tricky part. You cannot simply mount the ISO and run setup. Here is the step-by-step troubleshooting guide.
Step 1: Disable Real-Time Antivirus (Temporarily)
Step 2: Mount or Extract the ISO
Step 3: Run Setup as Administrator
Step 4: Apply the Crack (No-CD Fix)
Step 5: Compatibility Settings
Step 6: Install DirectX 9.0c and PhysX Legacy
Common Issues & Fixes:
Downloading this game as abandonware occupies a legal gray area. While EA will not sue you for a 14-year-old game with no commercial value, it is technically copyright infringement.