Switch to DuckStation (Windows/Linux/Android/macOS). It’s:
If you must use ePSXe (e.g., old plugins like Pete’s OGL2 for specific effects), batch convert your CHD collection to bin/cue and accept the larger file size. epsxe chd files
If you manage to get a build of ePSXe that experimental supports CHD, or you are converting back and forth, here is how to optimize your system. Switch to DuckStation (Windows/Linux/Android/macOS)
Here is where things get tricky. ePSXe 1.8.0, 1.9.0, and 2.0.5 do not support CHD files out of the box. If you download a .chd file and try to run it via File > Run ISO, ePSXe will look at the file extension, scratch its head, and return a "No disc loaded" error. If you must use ePSXe (e
ePSXe was developed primarily in the early 2000s and updated sporadically through the 2010s. CHD support became mainstream in emulators like DuckStation, PCSX-Reloaded, and RetroArch much later.