Strictly speaking, no. Microsoft does not provide a "highly compressed" Windows 10 ISO. However, there is one legitimate gray-area alternative: Tiny10 or Windows 10 LTSC (Legally stripped).
The user downloads a compressed archive (RAR/ZIP). Upon attempting to extract the file, the user is notified that the archive is "corrupt" or requires a password. To get the password, the user is redirected to a website demanding they complete a survey or "verify they are human." highly compressed windows 10 iso file download link
A: Run the VirusTotal and VM tests mentioned above. If you cannot verify its origin (e.g., direct from Microsoft servers), treat it as unsafe. Strictly speaking, no