Ensure your system has the latest versions of DirectX and Visual C++ Redistributable.
If deleting the INI didn't work, you need to manually dictate a resolution and refresh rate the game cannot refuse. serious sam 3 cannot set display mode
gfx_iScreenResolution (there are two entries: width and height).
gfx_iDisplayDevice.
gfx_iWindowedMode.
Running the game as an administrator can sometimes resolve permissions issues. Ensure your system has the latest versions of
The Serious Engine 3.5 has a known feud with Windows 10/11’s DPI virtualization and full-screen optimizations. Search for gfx_iDisplayDevice
SeriousSam3.exe and select Properties.This document walks through systematic steps to fix the error “Cannot set display mode” (or similar display-related errors) when launching Serious Sam 3 (BFE). Follow steps in order. Try launching the game after each step to check whether the issue is resolved.