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Hormones regulate behavior. Hypothyroidism in dogs is notorious for presenting as "lethargy and fear-biting." Conversely, hyperthyroidism in cats often mimics generalized anxiety—yowling at night, restlessness, and over-grooming.

Pain is a primary driver of behavior change. A 2017 study in the Journal of Veterinary Behavior found that over 80% of dogs referred for aggression toward family members had an underlying medical condition, most commonly orthopedic pain or dental disease. Hormones regulate behavior

The link between behavior and physiology varies dramatically across species. Hormones regulate behavior